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4lou

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==Structure of the E148Q mutant of CLC-ec1 deltaNC construct in the absence of halide==
==Structure of the E148Q mutant of CLC-ec1 deltaNC construct in the absence of halide==
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<StructureSection load='4lou' size='340' side='right' caption='[[4lou]], [[Resolution|resolution]] 2.98&Aring;' scene=''>
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<StructureSection load='4lou' size='340' side='right'caption='[[4lou]], [[Resolution|resolution]] 2.98&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4lou]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LOU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LOU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4lou]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LOU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LOU FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ene|4ene]], [[4kk8|4kk8]], [[1otu|1otu]], [[4kjq|4kjq]], [[4kk6|4kk6]], [[4kkc|4kkc]], [[4kkl|4kkl]]</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lou FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lou OCA], [https://pdbe.org/4lou PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lou RCSB], [https://www.ebi.ac.uk/pdbsum/4lou PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lou ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b0155, clcA, eriC, JW5012, yadQ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lou FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lou OCA], [http://pdbe.org/4lou PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lou RCSB], [http://www.ebi.ac.uk/pdbsum/4lou PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lou ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CLCA_ECOLI CLCA_ECOLI]] Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.<ref>PMID:12384697</ref> <ref>PMID:14985752</ref> <ref>PMID:16341087</ref> <ref>PMID:16905147</ref> <ref>PMID:18678918</ref>
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[https://www.uniprot.org/uniprot/CLCA_ECOLI CLCA_ECOLI] Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.<ref>PMID:12384697</ref> <ref>PMID:14985752</ref> <ref>PMID:16341087</ref> <ref>PMID:16905147</ref> <ref>PMID:18678918</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Lim, H H]]
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[[Category: Mus musculus]]
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[[Category: Miller, C]]
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[[Category: Lim H-H]]
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[[Category: Cl-/h+ antiporter]]
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[[Category: Miller C]]
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[[Category: Membrane protein]]
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[[Category: Tranport protein]]
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Revision as of 11:16, 14 December 2022

Structure of the E148Q mutant of CLC-ec1 deltaNC construct in the absence of halide

PDB ID 4lou

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