4lq5

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<StructureSection load='4lq5' size='340' side='right'caption='[[4lq5]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='4lq5' size='340' side='right'caption='[[4lq5]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4lq5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LQ5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4lq5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LQ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LQ5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OAS:O-ACETYLSERINE'>OAS</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OAS:O-ACETYLSERINE'>OAS</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4gwo|4gwo]], [[4gxa|4gxa]], [[4lon|4lon]], [[4lp2|4lp2]], [[4lq2|4lq2]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lq5 OCA], [https://pdbe.org/4lq5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lq5 RCSB], [https://www.ebi.ac.uk/pdbsum/4lq5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lq5 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cysB, STM1713 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=99287 SALTY])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lq5 OCA], [http://pdbe.org/4lq5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lq5 RCSB], [http://www.ebi.ac.uk/pdbsum/4lq5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lq5 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CYSB_SALTY CYSB_SALTY]] This protein is a positive regulator of gene expression for the cysteine regulon, a system of 10 or more loci involved in the biosynthesis of L-cysteine from inorganic sulfate. The inducer for CysB is N-acetylserine. CysB inhibits its own transcription.
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[https://www.uniprot.org/uniprot/CYSB_SALTY CYSB_SALTY] This protein is a positive regulator of gene expression for the cysteine regulon, a system of 10 or more loci involved in the biosynthesis of L-cysteine from inorganic sulfate. The inducer for CysB is N-acetylserine. CysB inhibits its own transcription.
==See Also==
==See Also==
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*[[Transcriptional activator|Transcriptional activator]]
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*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Salty]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
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[[Category: Kumaran, S]]
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[[Category: Kumaran S]]
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[[Category: Mittal, M]]
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[[Category: Mittal M]]
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[[Category: Singh, A K]]
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[[Category: Singh AK]]
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[[Category: Cytoplasmic]]
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[[Category: Dna binding]]
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[[Category: Gene regulation]]
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[[Category: Lttr]]
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[[Category: N-acetyl serine binding]]
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[[Category: O-acetyl serine]]
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[[Category: Rossmann fold]]
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[[Category: Transcriptional regulation]]
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[[Category: Whth motif/ pbp type ii alpha/beta fold]]
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Revision as of 11:18, 14 December 2022

Crystal structure of ligand binding domain of CysB, a LysR member from Salmonella typhimurium LT2 in complex with effector ligand, O-acetylserine at 2.8A

PDB ID 4lq5

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