8bi9

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'''Unreleased structure'''
 
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The entry 8bi9 is ON HOLD until Paper Publication
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==Structure of a cyclic beta-hairpin peptide derived from neuronal nitric oxide synthase (T112W/T116E variant)==
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<StructureSection load='8bi9' size='340' side='right'caption='[[8bi9]], [[Resolution|resolution]] 1.44&Aring;' scene=''>
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Authors: Balboa, J.R., Ostergaard, S., Stromgaard, K., Knapp, S., Joerger, A.C., Structural Genomics Consortium (SGC)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8bi9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BI9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BI9 FirstGlance]. <br>
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Description: Structure of a cyclic beta-hairpin peptide derived from neuronal nitric oxide synthase (T112W/T116E variant)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPR:D-PROLINE'>DPR</scene>, <scene name='pdbligand=TBU:TERTIARY-BUTYL+ALCOHOL'>TBU</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bi9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bi9 OCA], [https://pdbe.org/8bi9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bi9 RCSB], [https://www.ebi.ac.uk/pdbsum/8bi9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bi9 ProSAT]</span></td></tr>
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[[Category: Knapp, S]]
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</table>
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[[Category: Balboa, J.R]]
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== Function ==
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[[Category: Ostergaard, S]]
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[https://www.uniprot.org/uniprot/NOS1_HUMAN NOS1_HUMAN] Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
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[[Category: Joerger, A.C]]
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__TOC__
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[[Category: Structural Genomics Consortium (Sgc)]]
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</StructureSection>
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[[Category: Stromgaard, K]]
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Balboa JR]]
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[[Category: Joerger AC]]
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[[Category: Knapp S]]
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[[Category: Ostergaard S]]
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[[Category: Stromgaard K]]

Revision as of 09:28, 21 December 2022

Structure of a cyclic beta-hairpin peptide derived from neuronal nitric oxide synthase (T112W/T116E variant)

PDB ID 8bi9

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