8e4y
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of human glycerol-3-phosphate acyltransferase 1 (GPAT1) in complex with 2-oxohexadecyl-CoA== | |
| - | + | <StructureSection load='8e4y' size='340' side='right'caption='[[8e4y]], [[Resolution|resolution]] 3.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8e4y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8E4Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8E4Y FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NKO:(2R)-2-HYDROXY-3-(PHOSPHONOOXY)PROPYL+HEXADECANOATE'>NKO</scene>, <scene name='pdbligand=UKL:[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methyl+(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-{[3-oxo-3-({2-[(2-oxohexadecyl)sulfanyl]ethyl}amino)propyl]amino}butyl+dihydrogen+diphosphate+(non-preferred+name)'>UKL</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8e4y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8e4y OCA], [https://pdbe.org/8e4y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8e4y RCSB], [https://www.ebi.ac.uk/pdbsum/8e4y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8e4y ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GPAT1_HUMAN GPAT1_HUMAN] Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids.<ref>PMID:18238778</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ammirati M]] | ||
| + | [[Category: Chang JS]] | ||
| + | [[Category: Han S]] | ||
| + | [[Category: Johnson ZL]] | ||
| + | [[Category: Wasilko DJ]] | ||
| + | [[Category: Wu H]] | ||
Revision as of 09:30, 21 December 2022
Cryo-EM structure of human glycerol-3-phosphate acyltransferase 1 (GPAT1) in complex with 2-oxohexadecyl-CoA
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Categories: Homo sapiens | Large Structures | Ammirati M | Chang JS | Han S | Johnson ZL | Wasilko DJ | Wu H
