8e50
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Cryo-EM structure of human glycerol-3-phosphate acyltransferase 1 (GPAT1) in complex with CoA and palmitoyl-LPA== | |
- | + | <StructureSection load='8e50' size='340' side='right'caption='[[8e50]], [[Resolution|resolution]] 3.67Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[8e50]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8E50 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8E50 FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=NKO:(2R)-2-HYDROXY-3-(PHOSPHONOOXY)PROPYL+HEXADECANOATE'>NKO</scene></td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8e50 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8e50 OCA], [https://pdbe.org/8e50 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8e50 RCSB], [https://www.ebi.ac.uk/pdbsum/8e50 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8e50 ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/GPAT1_HUMAN GPAT1_HUMAN] Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids.<ref>PMID:18238778</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Ammirati M]] | ||
+ | [[Category: Chang JS]] | ||
+ | [[Category: Han S]] | ||
+ | [[Category: Johnson ZL]] | ||
+ | [[Category: Wasilko DJ]] | ||
+ | [[Category: Wu H]] |
Revision as of 09:30, 21 December 2022
Cryo-EM structure of human glycerol-3-phosphate acyltransferase 1 (GPAT1) in complex with CoA and palmitoyl-LPA
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Categories: Homo sapiens | Large Structures | Ammirati M | Chang JS | Han S | Johnson ZL | Wasilko DJ | Wu H