7z1z
From Proteopedia
(Difference between revisions)
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==MVV strand transfer complex (STC) intasome in complex with LEDGF/p75 at 3.5 A resolution== | ==MVV strand transfer complex (STC) intasome in complex with LEDGF/p75 at 3.5 A resolution== | ||
| - | <StructureSection load='7z1z' size='340' side='right'caption='[[7z1z]]' scene=''> | + | <StructureSection load='7z1z' size='340' side='right'caption='[[7z1z]], [[Resolution|resolution]] 3.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Z1Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Z1Z FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7z1z]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/DNA_molecule DNA molecule], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Visna/maedi_virus_EV1_KV1772 Visna/maedi virus EV1 KV1772]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Z1Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Z1Z FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7z1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7z1z OCA], [https://pdbe.org/7z1z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7z1z RCSB], [https://www.ebi.ac.uk/pdbsum/7z1z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7z1z ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7z1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7z1z OCA], [https://pdbe.org/7z1z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7z1z RCSB], [https://www.ebi.ac.uk/pdbsum/7z1z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7z1z ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/POL_VILVK POL_VILVK] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: DNA molecule]] | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Visna/maedi virus EV1 KV1772]] | ||
[[Category: Ballandras-Colas A]] | [[Category: Ballandras-Colas A]] | ||
[[Category: Cherepanov P]] | [[Category: Cherepanov P]] | ||
[[Category: Pye VE]] | [[Category: Pye VE]] | ||
Revision as of 10:12, 21 December 2022
MVV strand transfer complex (STC) intasome in complex with LEDGF/p75 at 3.5 A resolution
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