4m4w

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==Mechanistic implications for the bacterial primosome assembly of the structure of a helicase-helicase loader complex==
==Mechanistic implications for the bacterial primosome assembly of the structure of a helicase-helicase loader complex==
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<StructureSection load='4m4w' size='340' side='right' caption='[[4m4w]], [[Resolution|resolution]] 6.10&Aring;' scene=''>
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<StructureSection load='4m4w' size='340' side='right'caption='[[4m4w]], [[Resolution|resolution]] 6.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4m4w]] is a 15 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_12980 Atcc 12980] and [http://en.wikipedia.org/wiki/Bacsu Bacsu]. The December 2013 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''DNA Helicase'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2013_12 10.2210/rcsb_pdb/mom_2013_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M4W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M4W FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4m4w]] is a 15 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168] and [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. The December 2013 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''DNA Helicase'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2013_12 10.2210/rcsb_pdb/mom_2013_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M4W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M4W FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dnaB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1422 ATCC 12980]), dnaG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1422 ATCC 12980]), BSU28980, dnaI, ytxA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224308 BACSU])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m4w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m4w OCA], [https://pdbe.org/4m4w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m4w RCSB], [https://www.ebi.ac.uk/pdbsum/4m4w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m4w ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m4w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m4w OCA], [http://pdbe.org/4m4w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4m4w RCSB], [http://www.ebi.ac.uk/pdbsum/4m4w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4m4w ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DNAI_BACSU DNAI_BACSU]] Probably involved in DNA replication. [[http://www.uniprot.org/uniprot/PRIM_GEOSE PRIM_GEOSE]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis.
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[https://www.uniprot.org/uniprot/Q9X4C9_GEOSE Q9X4C9_GEOSE]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[RNA polymerase|RNA polymerase]]
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 12980]]
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[[Category: Bacillus subtilis subsp. subtilis str. 168]]
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[[Category: Bacsu]]
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[[Category: DNA Helicase]]
[[Category: DNA Helicase]]
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[[Category: Geobacillus stearothermophilus]]
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[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Eliason, W K]]
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[[Category: Eliason WK]]
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[[Category: Liu, B]]
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[[Category: Liu B]]
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[[Category: Steitz, T A]]
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[[Category: Steitz TA]]
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[[Category: Dna replication]]
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[[Category: Dnab]]
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[[Category: Dnag]]
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[[Category: Dnai]]
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[[Category: Helicase loader]]
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[[Category: Primase]]
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[[Category: Replication]]
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Revision as of 10:55, 21 December 2022

Mechanistic implications for the bacterial primosome assembly of the structure of a helicase-helicase loader complex

PDB ID 4m4w

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