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4m5u
From Proteopedia
(Difference between revisions)
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==5-(4-FLUOROPHENYL)-3-HYDROXY-6-[4-(1H-1,2,3,4-TETRAZOL-5-YL)PHENYL]-1,2-DIHYDROPYRIDIN-2-ONE bound to influenza 2009 pH1N1 endonuclease== | ==5-(4-FLUOROPHENYL)-3-HYDROXY-6-[4-(1H-1,2,3,4-TETRAZOL-5-YL)PHENYL]-1,2-DIHYDROPYRIDIN-2-ONE bound to influenza 2009 pH1N1 endonuclease== | ||
| - | <StructureSection load='4m5u' size='340' side='right' caption='[[4m5u]], [[Resolution|resolution]] 2.20Å' scene=''> | + | <StructureSection load='4m5u' size='340' side='right'caption='[[4m5u]], [[Resolution|resolution]] 2.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4m5u]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4m5u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/Lima/WRAIR1695P/2009(H1N1)) Influenza A virus (A/Lima/WRAIR1695P/2009(H1N1))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M5U FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=20F:5-(4-FLUOROPHENYL)-3-HYDROXY-6-[4-(1H-TETRAZOL-5-YL)PHENYL]PYRIDIN-2(1H)-ONE'>20F</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=20F:5-(4-FLUOROPHENYL)-3-HYDROXY-6-[4-(1H-TETRAZOL-5-YL)PHENYL]PYRIDIN-2(1H)-ONE'>20F</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m5u OCA], [https://pdbe.org/4m5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m5u RCSB], [https://www.ebi.ac.uk/pdbsum/4m5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m5u ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| - | == Function == | ||
| - | [[http://www.uniprot.org/uniprot/F0TRT1_9INFA F0TRT1_9INFA]] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication (By similarity).[SAAS:SAAS001009_004_020464] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Arnold | + | [[Category: Large Structures]] |
| - | [[Category: Bauman | + | [[Category: Arnold E]] |
| - | [[Category: Das | + | [[Category: Bauman JD]] |
| - | [[Category: Patel | + | [[Category: Das K]] |
| - | + | [[Category: Patel D]] | |
| - | + | ||
| - | + | ||
Revision as of 10:57, 21 December 2022
5-(4-FLUOROPHENYL)-3-HYDROXY-6-[4-(1H-1,2,3,4-TETRAZOL-5-YL)PHENYL]-1,2-DIHYDROPYRIDIN-2-ONE bound to influenza 2009 pH1N1 endonuclease
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Categories: Large Structures | Arnold E | Bauman JD | Das K | Patel D
