4mhv

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==Crystal structure of the PNT domain of human ETS2==
==Crystal structure of the PNT domain of human ETS2==
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<StructureSection load='4mhv' size='340' side='right' caption='[[4mhv]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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<StructureSection load='4mhv' size='340' side='right'caption='[[4mhv]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4mhv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MHV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MHV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4mhv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MHV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MHV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ETS2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mhv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mhv OCA], [https://pdbe.org/4mhv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mhv RCSB], [https://www.ebi.ac.uk/pdbsum/4mhv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mhv ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mhv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mhv OCA], [http://pdbe.org/4mhv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mhv RCSB], [http://www.ebi.ac.uk/pdbsum/4mhv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mhv ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ETS2_HUMAN ETS2_HUMAN]] Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.<ref>PMID:11909962</ref>
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[https://www.uniprot.org/uniprot/ETS2_HUMAN ETS2_HUMAN] Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.<ref>PMID:11909962</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H]]
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[[Category: Large Structures]]
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[[Category: Bountra, C]]
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[[Category: Arrowsmith CH]]
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[[Category: Burgess-brown, N]]
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[[Category: Bountra C]]
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[[Category: Cooper, C D.O]]
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[[Category: Burgess-brown N]]
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[[Category: Edwards, A]]
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[[Category: Cooper CDO]]
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[[Category: Gileadi, O]]
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[[Category: Edwards A]]
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[[Category: Krojer, T]]
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[[Category: Gileadi O]]
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[[Category: Newman, J A]]
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[[Category: Krojer T]]
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[[Category: Shrestha, L]]
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[[Category: Newman JA]]
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[[Category: Transcription]]
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[[Category: Shrestha L]]
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[[Category: Transcription factor]]
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Revision as of 09:39, 28 December 2022

Crystal structure of the PNT domain of human ETS2

PDB ID 4mhv

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