4mpg

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==Crystal structure of human glutathione transferase theta-2, complex with glutathione and unknown ligand, target EFI-507257==
==Crystal structure of human glutathione transferase theta-2, complex with glutathione and unknown ligand, target EFI-507257==
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<StructureSection load='4mpg' size='340' side='right' caption='[[4mpg]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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<StructureSection load='4mpg' size='340' side='right'caption='[[4mpg]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4mpg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MPG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4mpg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MPG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mpg OCA], [https://pdbe.org/4mpg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mpg RCSB], [https://www.ebi.ac.uk/pdbsum/4mpg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mpg ProSAT]</span></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mpf|4mpf]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GSTT2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mpg OCA], [http://pdbe.org/4mpg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mpg RCSB], [http://www.ebi.ac.uk/pdbsum/4mpg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mpg ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GST2_HUMAN GST2_HUMAN]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity.
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[https://www.uniprot.org/uniprot/GSTT2_HUMAN GSTT2_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity.
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==See Also==
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*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Glutathione transferase]]
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[[Category: Homo sapiens]]
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[[Category: Human]]
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[[Category: Large Structures]]
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[[Category: Almo, S C]]
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[[Category: Al Obaidi N]]
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[[Category: Armstrong, R N]]
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[[Category: Almo SC]]
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[[Category: Bhosle, R]]
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[[Category: Armstrong RN]]
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[[Category: Chowdhury, S]]
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[[Category: Bhosle R]]
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[[Category: EFI, Enzyme Function Initiative]]
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[[Category: Chowdhury S]]
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[[Category: Evans, B]]
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[[Category: Evans B]]
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[[Category: Gerlt, J A]]
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[[Category: Gerlt JA]]
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[[Category: Glenn, A Scott]]
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[[Category: Hammonds J]]
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[[Category: Hammonds, J]]
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[[Category: Hillerich B]]
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[[Category: Hillerich, B]]
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[[Category: Imker HJ]]
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[[Category: Imker, H J]]
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[[Category: Love J]]
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[[Category: Love, J]]
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[[Category: Patskovsky Y]]
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[[Category: Obaidi, N Al]]
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[[Category: Scott Glenn A]]
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[[Category: Patskovsky, Y]]
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[[Category: Seidel RD]]
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[[Category: Seidel, R D]]
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[[Category: Stead M]]
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[[Category: Stead, M]]
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[[Category: Toro R]]
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[[Category: Toro, R]]
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[[Category: Washington E]]
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[[Category: Washington, E]]
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[[Category: Efi]]
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[[Category: Enzyme function initiative]]
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[[Category: Glutathione s-transferase]]
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[[Category: Structural genomic]]
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[[Category: Transferase]]
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Revision as of 09:59, 28 December 2022

Crystal structure of human glutathione transferase theta-2, complex with glutathione and unknown ligand, target EFI-507257

PDB ID 4mpg

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