4mx7

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==Structure of mouse CD1d in complex with dioleoyl-phosphatidic acid==
==Structure of mouse CD1d in complex with dioleoyl-phosphatidic acid==
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<StructureSection load='4mx7' size='340' side='right' caption='[[4mx7]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
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<StructureSection load='4mx7' size='340' side='right'caption='[[4mx7]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4mx7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MX7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MX7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4mx7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MX7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MX7:(2R)-3-(PHOSPHONOOXY)PROPANE-1,2-DIYL+(9Z,9Z)BIS-OCTADEC-9-ENOATE'>MX7</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MX7:(2R)-3-(PHOSPHONOOXY)PROPANE-1,2-DIYL+(9Z,9Z)BIS-OCTADEC-9-ENOATE'>MX7</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zhn|1zhn]], [[2gaz|2gaz]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mx7 OCA], [https://pdbe.org/4mx7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mx7 RCSB], [https://www.ebi.ac.uk/pdbsum/4mx7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mx7 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cd1.1, Cd1d1, mcd1d ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice]), B2m ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mx7 OCA], [http://pdbe.org/4mx7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mx7 RCSB], [http://www.ebi.ac.uk/pdbsum/4mx7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mx7 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CD1D1_MOUSE CD1D1_MOUSE]] Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.<ref>PMID:11754812</ref> <ref>PMID:16314439</ref> <ref>PMID:16007091</ref> [[http://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
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[https://www.uniprot.org/uniprot/CD1D1_MOUSE CD1D1_MOUSE] Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.<ref>PMID:11754812</ref> <ref>PMID:16314439</ref> <ref>PMID:16007091</ref>
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==See Also==
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*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
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*[[CD1|CD1]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Wang, J]]
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[[Category: Mus musculus]]
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[[Category: Zajonc, D M]]
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[[Category: Wang J]]
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[[Category: Antigen presentation]]
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[[Category: Zajonc DM]]
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[[Category: Immune system]]
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[[Category: Lipid antigen]]
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[[Category: Membrane]]
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[[Category: Mhc fold]]
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Revision as of 10:16, 28 December 2022

Structure of mouse CD1d in complex with dioleoyl-phosphatidic acid

PDB ID 4mx7

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