1jjw
From Proteopedia
| Line 1: | Line 1: | ||
[[Image:1jjw.gif|left|200px]] | [[Image:1jjw.gif|left|200px]] | ||
| - | + | <!-- | |
| - | + | The line below this paragraph, containing "STRUCTURE_1jjw", creates the "Structure Box" on the page. | |
| - | + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | |
| - | + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | |
| - | + | or leave the SCENE parameter empty for the default display. | |
| - | + | --> | |
| - | + | {{STRUCTURE_1jjw| PDB=1jjw | SCENE= }} | |
| - | | | + | |
| - | + | ||
| - | }} | + | |
'''Structure of Haemophilus influenzae HslV Protein at 1.9 A Resolution''' | '''Structure of Haemophilus influenzae HslV Protein at 1.9 A Resolution''' | ||
| Line 27: | Line 24: | ||
[[Category: McKay, D B.]] | [[Category: McKay, D B.]] | ||
[[Category: Sousa, M C.]] | [[Category: Sousa, M C.]] | ||
| - | [[Category: | + | [[Category: K anomalous scattering]] |
| - | [[Category: | + | [[Category: Quasi-equivalent packing]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 21:18:46 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 18:18, 2 May 2008
Structure of Haemophilus influenzae HslV Protein at 1.9 A Resolution
Overview
The structure of the Haemophilus influenzae HslV protease of the HslUV 'prokaryotic proteasome' has been solved by molecular replacement and refined with data to 1.9 A resolution. The protease is a 'double donut' of hexameric rings; two alternative sets of intermolecular interactions between protomers in the rings result in 'quasi-equivalent' packing within the assembly. Anomalous scattering data from crystals with potassium present in the mother liquor reveal a K(+) ion bound with octahedral coordination near the active-site Thr1 residue. The site also binds Na(+) ions and is likely to bind Mg(2+), suggesting that monovalent and divalent metal ions may influence the catalytic activity of the protease.
About this Structure
1JJW is a Single protein structure of sequence from Haemophilus influenzae. Full crystallographic information is available from OCA.
Reference
Structure of Haemophilus influenzae HslV protein at 1.9 A resolution, revealing a cation-binding site near the catalytic site., Sousa MC, McKay DB, Acta Crystallogr D Biol Crystallogr. 2001 Dec;57(Pt 12):1950-4. Epub 2001, Nov 21. PMID:11717526 Page seeded by OCA on Fri May 2 21:18:46 2008
