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7rb3

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'''Unreleased structure'''
 
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The entry 7rb3 is ON HOLD
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==Cryo-EM structure of human binary NatC complex with a Bisubstrate inhibitor==
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<StructureSection load='7rb3' size='340' side='right'caption='[[7rb3]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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Authors: Deng, S., Marmorstein, R.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7rb3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RB3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RB3 FirstGlance]. <br>
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Description: Cryo-EM structure of human binary NatC complex with a Bisubstrate inhibitor
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMC:CARBOXYMETHYL+COENZYME+*A'>CMC</scene>, <scene name='pdbligand=LEU:LEUCINE'>LEU</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rb3 OCA], [https://pdbe.org/7rb3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rb3 RCSB], [https://www.ebi.ac.uk/pdbsum/7rb3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rb3 ProSAT]</span></td></tr>
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[[Category: Deng, S]]
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</table>
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[[Category: Marmorstein, R]]
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== Function ==
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[https://www.uniprot.org/uniprot/NAA35_HUMAN NAA35_HUMAN] Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Involved in regulation of apoptosis and proliferation of smooth muscle cells.<ref>PMID:19398576</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Deng S]]
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[[Category: Marmorstein R]]

Revision as of 07:31, 11 January 2023

Cryo-EM structure of human binary NatC complex with a Bisubstrate inhibitor

PDB ID 7rb3

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