1hje

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<StructureSection load='1hje' size='340' side='right'caption='[[1hje]], [[Resolution|resolution]] 0.75&Aring;' scene=''>
<StructureSection load='1hje' size='340' side='right'caption='[[1hje]], [[Resolution|resolution]] 0.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1hje]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HJE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HJE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1hje]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Conus_striatus Conus striatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HJE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HJE FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1qmw|1qmw]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hje FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hje OCA], [https://pdbe.org/1hje PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hje RCSB], [https://www.ebi.ac.uk/pdbsum/1hje PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hje ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hje FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hje OCA], [https://pdbe.org/1hje PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hje RCSB], [https://www.ebi.ac.uk/pdbsum/1hje PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hje ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/CAS1_CONST CAS1_CONST]] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin blocks muscular nAChRs alpha-1/gamma and alpha-1/delta subunits.
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[https://www.uniprot.org/uniprot/CAS1_CONST CAS1_CONST] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin blocks muscular nAChRs alpha-1/gamma and alpha-1/delta subunits.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Conus striatus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Barany, G]]
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[[Category: Barany G]]
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[[Category: Hargittai, B]]
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[[Category: Hargittai B]]
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[[Category: Janes, R W]]
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[[Category: Janes RW]]
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[[Category: Maclean, E J]]
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[[Category: Maclean EJ]]
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[[Category: Teat, S J]]
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[[Category: Teat SJ]]
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[[Category: Conotoxin]]
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[[Category: Nicotinic acetylcholine receptor]]
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[[Category: Toxin]]
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[[Category: Venom]]
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Revision as of 08:03, 11 January 2023

Crystal structure of alpha-conotoxin SI

PDB ID 1hje

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