2kgu

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==Spatial structure of purotoxin-1 in water==
==Spatial structure of purotoxin-1 in water==
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<StructureSection load='2kgu' size='340' side='right'caption='[[2kgu]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2kgu' size='340' side='right'caption='[[2kgu]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2kgu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Alomr Alomr]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KGU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KGU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2kgu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Alopecosa_marikovskyi Alopecosa marikovskyi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KGU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KGU FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">320151 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2066572 ALOMR])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kgu OCA], [https://pdbe.org/2kgu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kgu RCSB], [https://www.ebi.ac.uk/pdbsum/2kgu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kgu ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kgu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kgu OCA], [https://pdbe.org/2kgu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kgu RCSB], [https://www.ebi.ac.uk/pdbsum/2kgu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kgu ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TXPR1_ALOMR TXPR1_ALOMR] Inhibits P2RX3 receptors. Has an analgesic effect in rat. Enhances the high-affinity desensitization of P2RX3 receptors. At 50 nM, decreases the IC(50) for ambient ATP from 46.5 nM to 12.7 nM in mouse P2RX3.<ref>PMID:20437566</ref> <ref>PMID:22842000</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Alomr]]
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[[Category: Alopecosa marikovskyi]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arseniev, A]]
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[[Category: Arseniev A]]
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[[Category: Grishin, E]]
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[[Category: Grishin E]]
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[[Category: Korolkova, Y]]
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[[Category: Korolkova Y]]
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[[Category: Nadezhdin, K]]
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[[Category: Nadezhdin K]]
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[[Category: Pluzhnikov, K]]
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[[Category: Pluzhnikov K]]
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[[Category: Vassilevski, A]]
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[[Category: Vassilevski A]]
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[[Category: P2x receptor]]
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[[Category: Purotoxin-1]]
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[[Category: Toxin]]
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Revision as of 08:08, 11 January 2023

Spatial structure of purotoxin-1 in water

PDB ID 2kgu

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