4nci

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==Crystal Structure of Pyrococcus furiosis Rad50 R805E mutation==
==Crystal Structure of Pyrococcus furiosis Rad50 R805E mutation==
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<StructureSection load='4nci' size='340' side='right' caption='[[4nci]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='4nci' size='340' side='right'caption='[[4nci]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4nci]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrfu Pyrfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NCI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NCI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4nci]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NCI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NCI FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4nch|4nch]], [[4ncj|4ncj]], [[4nck|4nck]]</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nci OCA], [https://pdbe.org/4nci PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nci RCSB], [https://www.ebi.ac.uk/pdbsum/4nci PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nci ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PF1167, rad50 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=186497 PYRFU])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nci OCA], [http://pdbe.org/4nci PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nci RCSB], [http://www.ebi.ac.uk/pdbsum/4nci PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nci ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RAD50_PYRFU RAD50_PYRFU]] Involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and/or repositioning DNA ends into the Mre11 active site.[HAMAP-Rule:MF_00449]
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[https://www.uniprot.org/uniprot/RAD50_PYRFU RAD50_PYRFU] Involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and/or repositioning DNA ends into the Mre11 active site.[HAMAP-Rule:MF_00449]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4nci" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4nci" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[ATPase 3D structures|ATPase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Pyrfu]]
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[[Category: Large Structures]]
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[[Category: Arvai, A S]]
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[[Category: Pyrococcus furiosus DSM 3638]]
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[[Category: Classen, S]]
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[[Category: Arvai AS]]
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[[Category: Williams, G J]]
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[[Category: Classen S]]
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[[Category: Williams, R S]]
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[[Category: Williams GJ]]
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[[Category: Adenosine triphosphatase]]
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[[Category: Williams RS]]
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[[Category: Dna binding protein]]
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[[Category: Dna repair]]
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[[Category: Fungal protein]]
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Revision as of 08:22, 11 January 2023

Crystal Structure of Pyrococcus furiosis Rad50 R805E mutation

PDB ID 4nci

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