Signal recognition particle receptor

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'''Signal recognition particle receptor''' (SRPR) is associated with the endoplasmic reticulum. SRPR is a receptor for the [[Signal recognition particle protein|signal recognition particle (SRP)]]. SRPR is a heterodimer with α and β subunits which contain a GTP-binding domain. SRPR α subunit binds to SRP54 subunit of SRP complex. SRPR β subunit is a transmembrane GTPase. The bacterial SRPR is called '''FtsY'''.
'''Signal recognition particle receptor''' (SRPR) is associated with the endoplasmic reticulum. SRPR is a receptor for the [[Signal recognition particle protein|signal recognition particle (SRP)]]. SRPR is a heterodimer with α and β subunits which contain a GTP-binding domain. SRPR α subunit binds to SRP54 subunit of SRP complex. SRPR β subunit is a transmembrane GTPase. The bacterial SRPR is called '''FtsY'''.
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See also [[Intracellular receptors]]
*<scene name='48/485587/Cv/6'>GTP binding site</scene>. Water molecules are shown as red spheres.
*<scene name='48/485587/Cv/6'>GTP binding site</scene>. Water molecules are shown as red spheres.

Revision as of 09:23, 12 January 2023

Human SRPR α (magenta) and β subunit (deepskyblue) complex with GTP and Mg+2 (green) ion 2fh5

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3D structures of signal recognition particle receptor

Updated on 12-January-2023

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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