8fbh

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m (Protected "8fbh" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 8fbh is ON HOLD
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==Crystal structure of NSD1 Mutant-T1927A==
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<StructureSection load='8fbh' size='340' side='right'caption='[[8fbh]], [[Resolution|resolution]] 2.32&Aring;' scene=''>
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Authors: Providokhina, K., Dong, A., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8fbh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FBH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FBH FirstGlance]. <br>
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Description: Crystal structure of NSD1 Mutant-T1927A
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8fbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8fbh OCA], [https://pdbe.org/8fbh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8fbh RCSB], [https://www.ebi.ac.uk/pdbsum/8fbh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8fbh ProSAT]</span></td></tr>
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[[Category: Min, J]]
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</table>
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[[Category: Edwards, A.M]]
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== Function ==
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[[Category: Arrowsmith, C.H]]
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[https://www.uniprot.org/uniprot/NSD1_MOUSE NSD1_MOUSE] Histone methyltransferase. Preferentially methylates 'Lys-36' of histone H3 and 'Lys-20' of histone H4 (in vitro). Transcriptional intermediary factor capable of negatively influencing transcription. May also positively influence transcription. Essential for early post-implantation development.<ref>PMID:12805229</ref> <ref>PMID:9628876</ref>
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[[Category: Dong, A]]
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== References ==
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[[Category: Structural Genomics Consortium (Sgc)]]
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<references/>
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[[Category: Providokhina, K]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Arrowsmith CH]]
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[[Category: Dong A]]
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[[Category: Edwards AM]]
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[[Category: Min J]]
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[[Category: Providokhina K]]

Revision as of 07:34, 18 January 2023

Crystal structure of NSD1 Mutant-T1927A

PDB ID 8fbh

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