4nz9

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<StructureSection load='4nz9' size='340' side='right'caption='[[4nz9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='4nz9' size='340' side='right'caption='[[4nz9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4nz9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staa3 Staa3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NZ9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NZ9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4nz9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_USA300 Staphylococcus aureus subsp. aureus USA300]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NZ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NZ9 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1JT:1-(4-METHOXY-3-METHYLBENZYL)-5,6,7,8-TETRAHYDRO-1H-NAPHTHO[2,3-D]IMIDAZOLE'>1JT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1JT:1-(4-METHOXY-3-METHYLBENZYL)-5,6,7,8-TETRAHYDRO-1H-NAPHTHO[2,3-D]IMIDAZOLE'>1JT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fabi, SAUSA300_0912 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=367830 STAA3])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nz9 OCA], [https://pdbe.org/4nz9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nz9 RCSB], [https://www.ebi.ac.uk/pdbsum/4nz9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nz9 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADPH,_Re-specific) Enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.39 1.3.1.39] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nz9 OCA], [http://pdbe.org/4nz9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nz9 RCSB], [http://www.ebi.ac.uk/pdbsum/4nz9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nz9 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A0H2XIJ1_STAA3 A0A0H2XIJ1_STAA3]
==See Also==
==See Also==
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*[[Enoyl-Acyl-Carrier Protein Reductase|Enoyl-Acyl-Carrier Protein Reductase]]
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*[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Staa3]]
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[[Category: Staphylococcus aureus subsp. aureus USA300]]
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[[Category: Johnson, M E]]
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[[Category: Johnson ME]]
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[[Category: Mehboob, S]]
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[[Category: Mehboob S]]
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[[Category: Santarsiero, B D]]
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[[Category: Santarsiero BD]]
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[[Category: Nadph]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
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[[Category: Reductase]]
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[[Category: Reduction]]
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[[Category: Rossmann fold]]
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Revision as of 08:47, 18 January 2023

Crystal Structure of FabI from S. aureus in complex with a novel benzimidazole inhibitor

PDB ID 4nz9

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