8b3b
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of metacyclic VSG (mVSG) 531 from Trypanosoma brucei== | |
| - | + | <StructureSection load='8b3b' size='340' side='right'caption='[[8b3b]], [[Resolution|resolution]] 1.95Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8b3b]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8B3B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8B3B FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8b3b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8b3b OCA], [https://pdbe.org/8b3b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8b3b RCSB], [https://www.ebi.ac.uk/pdbsum/8b3b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8b3b ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/M4SYA9_9TRYP M4SYA9_9TRYP] VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.[ARBA:ARBA00002523] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Trypanosoma brucei]] | ||
| + | [[Category: Chandra M]] | ||
| + | [[Category: Stebbins CE]] | ||
Revision as of 06:34, 25 January 2023
Structure of metacyclic VSG (mVSG) 531 from Trypanosoma brucei
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