8hy5
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of D-amino acid oxidase mutant R38H== | |
| - | + | <StructureSection load='8hy5' size='340' side='right'caption='[[8hy5]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8hy5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HY5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HY5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hy5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hy5 OCA], [https://pdbe.org/8hy5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hy5 RCSB], [https://www.ebi.ac.uk/pdbsum/8hy5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hy5 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/OXDA_HUMAN OXDA_HUMAN] Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.<ref>PMID:17303072</ref> |
| - | [[Category: Khan | + | == References == |
| - | [[Category: Kumar | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Dave U]] | ||
| + | [[Category: Gomes J]] | ||
| + | [[Category: Khan S]] | ||
| + | [[Category: Kumar A]] | ||
| + | [[Category: Upadhyay S]] | ||
Revision as of 06:38, 25 January 2023
Structure of D-amino acid oxidase mutant R38H
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Categories: Homo sapiens | Large Structures | Dave U | Gomes J | Khan S | Kumar A | Upadhyay S
