3bby
From Proteopedia
(Difference between revisions)
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<StructureSection load='3bby' size='340' side='right'caption='[[3bby]], [[Resolution|resolution]] 1.85Å' scene=''> | <StructureSection load='3bby' size='340' side='right'caption='[[3bby]], [[Resolution|resolution]] 1.85Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3bby]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3bby]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BBY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BBY FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ETX:2-ETHOXYETHANOL'>ETX</scene> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ETX:2-ETHOXYETHANOL'>ETX</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bby OCA], [https://pdbe.org/3bby PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bby RCSB], [https://www.ebi.ac.uk/pdbsum/3bby PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bby ProSAT], [https://www.topsan.org/Proteins/JCSG/3bby TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bby OCA], [https://pdbe.org/3bby PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bby RCSB], [https://www.ebi.ac.uk/pdbsum/3bby PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bby ProSAT], [https://www.topsan.org/Proteins/JCSG/3bby TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/YFCF_ECOLI YFCF_ECOLI] Exhibits glutathione (GSH) S-transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB); however this activity is as low as 1% of that of GstA. Also displays a GSH-dependent peroxidase activity toward cumene hydroperoxide. Is involved in defense against oxidative stress, probably via its peroxidase activity. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Escherichia coli K-12]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Glutathione s-transferase]] | ||
| - | [[Category: Jcsg]] | ||
| - | [[Category: N-terminal domain]] | ||
| - | [[Category: Np_416804 1]] | ||
| - | [[Category: PSI, Protein structure initiative]] | ||
| - | [[Category: Transferase]] | ||
Revision as of 06:51, 25 January 2023
Crystal structure of glutathione S-transferase (NP_416804.1) from Escherichia coli K12 at 1.85 A resolution
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