4o9u

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<StructureSection load='4o9u' size='340' side='right'caption='[[4o9u]], [[Resolution|resolution]] 6.93&Aring;' scene=''>
<StructureSection load='4o9u' size='340' side='right'caption='[[4o9u]], [[Resolution|resolution]] 6.93&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4o9u]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet2 Thet2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O9U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O9U FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4o9u]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB27 Thermus thermophilus HB27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O9U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O9U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TT_C1779 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=262724 THET2]), TT_C1778 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=262724 THET2]), TT_C1780 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=262724 THET2])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o9u OCA], [https://pdbe.org/4o9u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o9u RCSB], [https://www.ebi.ac.uk/pdbsum/4o9u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o9u ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(P)(+)_transhydrogenase_(Re/Si-specific) NAD(P)(+) transhydrogenase (Re/Si-specific)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.1.2 1.6.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o9u OCA], [http://pdbe.org/4o9u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4o9u RCSB], [http://www.ebi.ac.uk/pdbsum/4o9u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4o9u ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/Q72GS0_THET2 Q72GS0_THET2]] The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity).[PIRNR:PIRNR000204]
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[https://www.uniprot.org/uniprot/Q72GR9_THET2 Q72GR9_THET2]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[NAD(P) transhydrogenase|NAD(P) transhydrogenase]]
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*[[NAD(P) transhydrogenase 3D structures|NAD(P) transhydrogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Thet2]]
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[[Category: Thermus thermophilus HB27]]
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[[Category: Carragher, B]]
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[[Category: Carragher B]]
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[[Category: Gennis, R B]]
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[[Category: Gennis RB]]
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[[Category: Leung, J H]]
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[[Category: Leung JH]]
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[[Category: Moeller, A]]
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[[Category: Moeller A]]
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[[Category: Potter, C S]]
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[[Category: Potter CS]]
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[[Category: Schurig-Briccio, L A]]
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[[Category: Schurig-Briccio LA]]
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[[Category: Stout, C D]]
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[[Category: Stout CD]]
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[[Category: Yamaguchi, M]]
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[[Category: Yamaguchi M]]
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[[Category: Alpha2]]
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[[Category: And domain iii as a dimer]]
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[[Category: Couples proton motive]]
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[[Category: Holo-transhydrogease from thermus thermophilus assembled from subunits alpha1]]
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[[Category: Hydride transfer]]
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[[Category: Membrane protein]]
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[[Category: Nicotinamide nucleotide transhydrogenase]]
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[[Category: Periplasmic membrane and cytosol]]
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[[Category: Proton translocation and hydride transfer]]
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[[Category: Truncated beta]]
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Revision as of 07:13, 25 January 2023

Mechanism of transhydrogenase coupling proton translocation and hydride transfer

PDB ID 4o9u

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