4ogq

From Proteopedia

(Difference between revisions)

Revision as of 07:24, 25 January 2023

Internal Lipid Architecture of the Hetero-Oligomeric Cytochrome b6f Complex

Structural highlights

4ogq is a 8 chain structure with sequence from Nostoc sp. PCC 7120 = FACHB-418. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	, , , , , , , , , , , , , , , ,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CYB6_NOSS1 Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity).

Publication Abstract from PubMed

The role of lipids in the assembly, structure, and function of hetero-oligomeric membrane protein complexes is poorly understood. The dimeric photosynthetic cytochrome b6f complex, a 16-mer of eight distinct subunits and 26 transmembrane helices, catalyzes transmembrane proton-coupled electron transfer for energy storage. Using a 2.5 A crystal structure of the dimeric complex, we identified 23 distinct lipid-binding sites per monomer. Annular lipids are proposed to provide a connection for super-complex formation with the photosystem-I reaction center and the LHCII kinase enzyme for transmembrane signaling. Internal lipids mediate crosslinking to stabilize the domain-swapped iron-sulfur protein subunit, dielectric heterogeneity within intermonomer and intramonomer electron transfer pathways, and dimer stabilization through lipid-mediated intermonomer interactions. This study provides a complete structure analysis of lipid-mediated functions in a multi-subunit membrane protein complex and reveals lipid sites at positions essential for assembly and function.

Internal Lipid Architecture of the Hetero-Oligomeric Cytochrome b6f Complex.,Hasan SS, Cramer WA Structure. 2014 Jul 8;22(7):1008-15. doi: 10.1016/j.str.2014.05.004. Epub 2014, Jun 12. PMID:24931468^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Hasan SS, Cramer WA. Internal Lipid Architecture of the Hetero-Oligomeric Cytochrome b6f Complex. Structure. 2014 Jul 8;22(7):1008-15. doi: 10.1016/j.str.2014.05.004. Epub 2014, Jun 12. PMID:24931468 doi:http://dx.doi.org/10.1016/j.str.2014.05.004

1 Structural highlights
2 Function
3 Publication Abstract from PubMed
4 See Also
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4ogq"

Categories: Large Structures | Nostoc sp. PCC 7120 = FACHB-418 | Cramer WA | Hasan SS

@@ Line 3: / Line 3: @@
 <StructureSection load='4ogq' size='340' side='right'caption='[[4ogq]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4ogq]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Nostoc_sp. Nostoc sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OGQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OGQ FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4ogq]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Nostoc_sp._PCC_7120_=_FACHB-418 Nostoc sp. PCC 7120 = FACHB-418]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OGQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OGQ FirstGlance]. <br>
 </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1O2:(2S)-3-(ALPHA-D-GALACTOPYRANOSYLOXY)-2-(HEXADECANOYLOXY)PROPYL+(9Z)-OCTADEC-9-ENOATE'>1O2</scene>, <scene name='pdbligand=2WA:(1S,8E)-1-{[(2S)-1-HYDROXY-3-{[(1S)-1-HYDROXYPENTADECYL]OXY}PROPAN-2-YL]OXY}HEPTADEC-8-EN-1-OL'>2WA</scene>, <scene name='pdbligand=2WD:(1R)-1-{[(2S)-3-HYDROXY-2-{[(1R)-1-HYDROXYPENTYL]OXY}PROPYL]OXY}HEXAN-1-OL'>2WD</scene>, <scene name='pdbligand=2WM:(1S,8E)-1-{[(2S)-3-HYDROXY-2-{[(1S)-1-HYDROXYOCTADECYL]OXY}PROPYL]OXY}OCTADEC-8-EN-1-OL'>2WM</scene>, <scene name='pdbligand=3WM:(1S,8E,1R,8Z)-1,1-{[(2S)-3-HYDROXYPROPANE-1,2-DIYL]BIS(OXY)}BISOCTADEC-8-EN-1-OL'>3WM</scene>, <scene name='pdbligand=7PH:(1R)-2-(DODECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL+TETRADECANOATE'>7PH</scene>, <scene name='pdbligand=8K6:OCTADECANE'>8K6</scene>, <scene name='pdbligand=BCR:BETA-CAROTENE'>BCR</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CLA:CHLOROPHYLL+A'>CLA</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=MYS:PENTADECANE'>MYS</scene>, <scene name='pdbligand=OCT:N-OCTANE'>OCT</scene>, <scene name='pdbligand=OPC:(7R,17E)-4-HYDROXY-N,N,N,7-TETRAMETHYL-7-[(8E)-OCTADEC-8-ENOYLOXY]-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOS-17-EN-1-AMINIUM+4-OXIDE'>OPC</scene>, <scene name='pdbligand=SQD:1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL'>SQD</scene>, <scene name='pdbligand=UMQ:UNDECYL-MALTOSIDE'>UMQ</scene></td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1vf5|1vf5]], [[1q90|1q90]], [[2e74|2e74]], [[2e75|2e75]], [[2e76|2e76]], [[2zt9|2zt9]], [[4h44|4h44]], [[4h13|4h13]], [[4h0l|4h0l]], [[3cx5|3cx5]]</div></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Plastoquinol--plastocyanin_reductase Plastoquinol--plastocyanin reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.9.1 1.10.9.1] </span></td></tr>
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ogq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ogq OCA], [https://pdbe.org/4ogq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ogq RCSB], [https://www.ebi.ac.uk/pdbsum/4ogq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ogq ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[https://www.uniprot.org/uniprot/PETM_NOSS1 PETM_NOSS1]] Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity). [[https://www.uniprot.org/uniprot/CYF_NOSS1 CYF_NOSS1]] Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity). [[https://www.uniprot.org/uniprot/PETG_NOSS1 PETG_NOSS1]] Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assembly of the cytochrome b6-f complex (By similarity). [[https://www.uniprot.org/uniprot/PETD_NOSS1 PETD_NOSS1]] Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity). [[https://www.uniprot.org/uniprot/PETN_NOSS1 PETN_NOSS1]] Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity). [[https://www.uniprot.org/uniprot/CYB6_NOSS1 CYB6_NOSS1]] Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity). [[https://www.uniprot.org/uniprot/UCRIA_NOSS1 UCRIA_NOSS1]] Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity). [[https://www.uniprot.org/uniprot/PETL_NOSS1 PETL_NOSS1]] Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex (By similarity).
+[https://www.uniprot.org/uniprot/CYB6_NOSS1 CYB6_NOSS1] Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity).
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 28: / Line 26: @@
 </StructureSection>
 [[Category: Large Structures]]
-[[Category: Nostoc sp]]
+[[Category: Nostoc sp. PCC 7120 = FACHB-418]]
-[[Category: Plastoquinol--plastocyanin reductase]]
+[[Category: Cramer WA]]
-[[Category: Cramer, W A]]
+[[Category: Hasan SS]]
-[[Category: Hasan, S S]]
-[[Category: Cytochrome c6]]
-[[Category: Electron transfer]]
-[[Category: Electron transport]]
-[[Category: Plastocyanin]]
-[[Category: Thylakoid membrane]]

4ogq

From Proteopedia

Revision as of 07:24, 25 January 2023

Internal Lipid Architecture of the Hetero-Oligomeric Cytochrome b6f Complex

Structural highlights

Function

Publication Abstract from PubMed

See Also

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

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