4okg

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<StructureSection load='4okg' size='340' side='right'caption='[[4okg]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
<StructureSection load='4okg' size='340' side='right'caption='[[4okg]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4okg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OKG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OKG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4okg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OKG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OKG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2SZ:6-(1H-BENZIMIDAZOL-1-YL)-N-HYDROXY-5-[4-({6-[(4-METHYLPIPERAZIN-1-YL)METHYL]PYRIDIN-3-YL}ETHYNYL)PHENYL]PYRIDINE-3-CARBOXAMIDE'>2SZ</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2SZ:6-(1H-BENZIMIDAZOL-1-YL)-N-HYDROXY-5-[4-({6-[(4-METHYLPIPERAZIN-1-YL)METHYL]PYRIDIN-3-YL}ETHYNYL)PHENYL]PYRIDINE-3-CARBOXAMIDE'>2SZ</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">envA, lpxC, PA4406 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4okg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4okg OCA], [https://pdbe.org/4okg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4okg RCSB], [https://www.ebi.ac.uk/pdbsum/4okg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4okg ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4okg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4okg OCA], [http://pdbe.org/4okg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4okg RCSB], [http://www.ebi.ac.uk/pdbsum/4okg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4okg ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LPXC_PSEAE LPXC_PSEAE]] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
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[https://www.uniprot.org/uniprot/LPXC_PSEAE LPXC_PSEAE] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pseae]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Lahiri, S D]]
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[[Category: Lahiri SD]]
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[[Category: Olivier, N B]]
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[[Category: Olivier NB]]
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[[Category: Prince, D B]]
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[[Category: Prince DB]]
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[[Category: Beta-alpha-alpha-beta sandwich]]
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[[Category: Cytoplasm]]
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[[Category: Deacetylase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Hydroxamate]]
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[[Category: Intracellular]]
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Revision as of 07:30, 25 January 2023

LpxC from P.aeruginosa with the inhibitor 6-(benzimidazol-1-yl)-5-[4-[2-[6-[(4-methylpiperazin-1-yl)methyl]-3-pyridyl]ethynyl]phenyl]pyridine-3-carbohydroxamic acid

PDB ID 4okg

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