4osd

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==Dimer of a C-terminal fragment of phage T4 gp5 beta-helix==
==Dimer of a C-terminal fragment of phage T4 gp5 beta-helix==
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<StructureSection load='4osd' size='340' side='right' caption='[[4osd]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
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<StructureSection load='4osd' size='340' side='right'caption='[[4osd]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4osd]] is a 18 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OSD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OSD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4osd]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OSD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OSD FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ELA:9-OCTADECENOIC+ACID'>ELA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene>, <scene name='pdbligand=STE:STEARIC+ACID'>STE</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ELA:9-OCTADECENOIC+ACID'>ELA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene>, <scene name='pdbligand=STE:STEARIC+ACID'>STE</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1k28|1k28]], [[4jj2|4jj2]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4osd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4osd OCA], [https://pdbe.org/4osd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4osd RCSB], [https://www.ebi.ac.uk/pdbsum/4osd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4osd ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4osd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4osd OCA], [http://pdbe.org/4osd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4osd RCSB], [http://www.ebi.ac.uk/pdbsum/4osd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4osd ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/VG05_BPT4 VG05_BPT4]] Tail-associated lysozyme essential for localized hydrolysis of bacterial cell wall necessary for viral DNA injection. The needle-like gp5 protein punctures the outer cell membrane and then digests the peptidoglycan cell wall in the periplasmic space.
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[https://www.uniprot.org/uniprot/NEEDL_BPT4 NEEDL_BPT4] Tail-associated lysozyme of the baseplate hub that is essential for localized hydrolysis of bacterial cell wall necessary for viral DNA injection. The needle-like gp5 protein punctures the outer cell membrane and then digests the peptidoglycan cell wall in the periplasmic space. Involved in the tail assembly.<ref>PMID:12837775</ref> <ref>PMID:21129200</ref>
==See Also==
==See Also==
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bpt4]]
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[[Category: Escherichia virus T4]]
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[[Category: Lysozyme]]
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[[Category: Large Structures]]
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[[Category: Buth, S A]]
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[[Category: Buth SA]]
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[[Category: Leiman, P G]]
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[[Category: Leiman PG]]
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[[Category: Shneider, M M]]
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[[Category: Shneider MM]]
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[[Category: Donor strand exchange]]
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[[Category: Fragment]]
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[[Category: Gp27-gp5 complex]]
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[[Category: Gp5 4]]
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[[Category: Hydrolase]]
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[[Category: Membrane piercing]]
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[[Category: Membrane piercing complex]]
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[[Category: Sds resistant]]
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[[Category: T4 gp5]]
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[[Category: Triple beta-helix]]
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Revision as of 07:43, 25 January 2023

Dimer of a C-terminal fragment of phage T4 gp5 beta-helix

PDB ID 4osd

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