4ovg
From Proteopedia
(Difference between revisions)
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==E. coli sliding clamp in complex with (R)-9-(2-amino-2-oxoethyl)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid== | ==E. coli sliding clamp in complex with (R)-9-(2-amino-2-oxoethyl)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid== | ||
- | <StructureSection load='4ovg' size='340' side='right' caption='[[4ovg]], [[Resolution|resolution]] 1.90Å' scene=''> | + | <StructureSection load='4ovg' size='340' side='right'caption='[[4ovg]], [[Resolution|resolution]] 1.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[4ovg]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4ovg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_str._K-12_substr._MC4100 Escherichia coli str. K-12 substr. MC4100]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OVG FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2VF:(2R)-9-(2-AMINO-2-OXOETHYL)-6-CHLORO-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-2-CARBOXYLIC+ACID'>2VF</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2VF:(2R)-9-(2-AMINO-2-OXOETHYL)-6-CHLORO-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-2-CARBOXYLIC+ACID'>2VF</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ovg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ovg OCA], [https://pdbe.org/4ovg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ovg RCSB], [https://www.ebi.ac.uk/pdbsum/4ovg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ovg ProSAT]</span></td></tr> | |
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- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
- | == Function == | ||
- | [[http://www.uniprot.org/uniprot/U6NCW5_ECOLI U6NCW5_ECOLI]] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA (By similarity).[PIRNR:PIRNR000804] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 4ovg" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4ovg" style="background-color:#fffaf0;"></div> | ||
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- | ==See Also== | ||
- | *[[DNA polymerase|DNA polymerase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | + | [[Category: Escherichia coli str. K-12 substr. MC4100]] | |
- | [[Category: Escherichia coli str. | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Oakley AJ]] |
- | [[Category: | + | [[Category: Yin Z]] |
- | [[Category: | + | |
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Revision as of 07:47, 25 January 2023
E. coli sliding clamp in complex with (R)-9-(2-amino-2-oxoethyl)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid
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