4owz
From Proteopedia
(Difference between revisions)
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<StructureSection load='4owz' size='340' side='right'caption='[[4owz]], [[Resolution|resolution]] 1.47Å' scene=''> | <StructureSection load='4owz' size='340' side='right'caption='[[4owz]], [[Resolution|resolution]] 1.47Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4owz]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4owz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OWZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OWZ FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4owz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4owz OCA], [https://pdbe.org/4owz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4owz RCSB], [https://www.ebi.ac.uk/pdbsum/4owz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4owz ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/ECP_HUMAN ECP_HUMAN] Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.<ref>PMID:2501794</ref> <ref>PMID:19450231</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Blanco | + | [[Category: Blanco JA]] |
| - | [[Category: Boix | + | [[Category: Boix E]] |
| - | [[Category: Moussaoui | + | [[Category: Moussaoui M]] |
| - | [[Category: Salazar | + | [[Category: Salazar VA]] |
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Revision as of 07:49, 25 January 2023
Structure of ECP/H15A mutant.
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