7qwv

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'''Unreleased structure'''
 
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The entry 7qwv is ON HOLD until Paper Publication
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==Crystal structure of the REC114-TOPOVIBL complex.==
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<StructureSection load='7qwv' size='340' side='right'caption='[[7qwv]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
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Authors: Juarez-Martinez, A.B., Robert, T., de Massy, B., Kadlec, J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7qwv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QWV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QWV FirstGlance]. <br>
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Description: Crystal structure of the REC114-TOPOVIBL complex.
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qwv OCA], [https://pdbe.org/7qwv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qwv RCSB], [https://www.ebi.ac.uk/pdbsum/7qwv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qwv ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Kadlec, J]]
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== Function ==
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[[Category: De Massy, B]]
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[https://www.uniprot.org/uniprot/RE114_MOUSE RE114_MOUSE] Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination (PubMed:20551173, PubMed:27723721). Probably acts by forming a complex with IHO1/CCDC36 and MEI4, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis (PubMed:27723721).<ref>PMID:20551173</ref> <ref>PMID:27723721</ref>
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[[Category: Robert, T]]
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== References ==
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[[Category: Juarez-Martinez, A.B]]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Juarez-Martinez AB]]
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[[Category: Kadlec J]]
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[[Category: Robert T]]
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[[Category: De Massy B]]

Revision as of 11:14, 1 February 2023

Crystal structure of the REC114-TOPOVIBL complex.

PDB ID 7qwv

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