7ytc
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of human FcmR bound to IgM-Fc/J== | |
| - | + | <StructureSection load='7ytc' size='340' side='right'caption='[[7ytc]], [[Resolution|resolution]] 3.39Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7ytc]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YTC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YTC FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ytc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ytc OCA], [https://pdbe.org/7ytc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ytc RCSB], [https://www.ebi.ac.uk/pdbsum/7ytc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ytc ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IGJ_HUMAN IGJ_HUMAN] Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.[UniProtKB:P01592] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Li Y]] | ||
| + | [[Category: Shen H]] | ||
| + | [[Category: Xiao J]] | ||
Revision as of 11:18, 1 February 2023
Cryo-EM structure of human FcmR bound to IgM-Fc/J
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Categories: Homo sapiens | Large Structures | Li Y | Shen H | Xiao J
