8arh
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==In situ subtomogram average of Vaccinia virus (WR) D13 lattice, on immature virions== | |
| - | + | <StructureSection load='8arh' size='340' side='right'caption='[[8arh]], [[Resolution|resolution]] 19.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8arh]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus_WR Vaccinia virus WR]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ARH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ARH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8arh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8arh OCA], [https://pdbe.org/8arh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8arh RCSB], [https://www.ebi.ac.uk/pdbsum/8arh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8arh ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/D13_VACCW D13_VACCW] Scaffold protein which forms a transitory spherical honeycomb lattice providing curvature and rigidity to the convex membrane of crescent and immature virions (IV). This association occurs concomitantly with viral membrane formation. Targeted by the drug rifampicin, which prevents the formation of this lattice, and hence virus morphogenesis. In the presence of rifampicin, irregularly shaped membranes that lack the honeycomb layer accumulate around areas of electron-dense viroplasm. This layer is lost from virions during maturation from IV to mature virion (MV), through the proteolysis of A17 N-terminus. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Vaccinia virus WR]] | ||
| + | [[Category: Calcraft T]] | ||
| + | [[Category: Hernandez-Gonzalez M]] | ||
| + | [[Category: Nans A]] | ||
| + | [[Category: Rosenthal PB]] | ||
| + | [[Category: Way M]] | ||
Revision as of 11:19, 1 February 2023
In situ subtomogram average of Vaccinia virus (WR) D13 lattice, on immature virions
| |||||||||||
