1jrg

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[[Image:1jrg.jpg|left|200px]]
[[Image:1jrg.jpg|left|200px]]
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{{Structure
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<!--
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|PDB= 1jrg |SIZE=350|CAPTION= <scene name='initialview01'>1jrg</scene>, resolution 2.1&Aring;
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The line below this paragraph, containing "STRUCTURE_1jrg", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Pectate_lyase Pectate lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.2.2 4.2.2.2] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= PELA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=556 Erwinia chrysanthemi])
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-->
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|DOMAIN=
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{{STRUCTURE_1jrg| PDB=1jrg | SCENE= }}
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|RELATEDENTRY=[[1jta|1JTA]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jrg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jrg OCA], [http://www.ebi.ac.uk/pdbsum/1jrg PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1jrg RCSB]</span>
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}}
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'''Crystal Structure of the R3 form of Pectate Lyase A, Erwinia chrysanthemi'''
'''Crystal Structure of the R3 form of Pectate Lyase A, Erwinia chrysanthemi'''
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[[Category: Thomas, L M.]]
[[Category: Thomas, L M.]]
[[Category: Yoder, M D.]]
[[Category: Yoder, M D.]]
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[[Category: parallel beta helix beta elimination]]
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[[Category: Parallel beta helix beta elimination]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 21:44:53 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:37:53 2008''
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Revision as of 18:44, 2 May 2008

Image:1jrg.jpg

Template:STRUCTURE 1jrg

Crystal Structure of the R3 form of Pectate Lyase A, Erwinia chrysanthemi


Overview

Pectate lyase A is a virulence factor secreted by the plant-pathogenic bacteria Erwinia chrysanthemi. The enzyme cleaves the glycosidic bond of pectate polymers by a calcium-dependent beta-elimination mechanism. The crystal structure of pectate lyase A from E. chrysanthemi EC16 has been determined in two crystal forms, monoclinic C2 to 1.8 A and rhombohedral R3 to 2.1 A. The protein structure is compared with two other pectate lyase isoforms from E. chrysanthemi EC16, pectate lyase C and pectate lyase E. Pectate lyase A is unique as it is the only acidic pectate lyase and has end products that are significantly more varied in length in comparison to those of the other four major pectate lyase isozymes. Differences and similarities in polypeptide trace, size and volume of the active-site groove and surface electrostatics are discussed.

About this Structure

1JRG is a Single protein structure of sequence from Erwinia chrysanthemi. Full crystallographic information is available from OCA.

Reference

Structure of pectate lyase A: comparison to other isoforms., Thomas LM, Doan CN, Oliver RL, Yoder MD, Acta Crystallogr D Biol Crystallogr. 2002 Jun;58(Pt 6 Pt 2):1008-15. Epub, 2002 May 29. PMID:12037303 Page seeded by OCA on Fri May 2 21:44:53 2008

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