3f9t

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Current revision (11:36, 1 February 2023) (edit) (undo)
 
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<StructureSection load='3f9t' size='340' side='right'caption='[[3f9t]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
<StructureSection load='3f9t' size='340' side='right'caption='[[3f9t]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3f9t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43067 Atcc 43067]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F9T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F9T FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3f9t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F9T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F9T FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mfnA, MJ0050, NP_247014.1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Tyrosine_decarboxylase Tyrosine decarboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.25 4.1.1.25] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f9t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f9t OCA], [https://pdbe.org/3f9t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f9t RCSB], [https://www.ebi.ac.uk/pdbsum/3f9t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f9t ProSAT], [https://www.topsan.org/Proteins/JCSG/3f9t TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f9t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f9t OCA], [https://pdbe.org/3f9t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f9t RCSB], [https://www.ebi.ac.uk/pdbsum/3f9t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f9t ProSAT], [https://www.topsan.org/Proteins/JCSG/3f9t TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/MFNA_METJA MFNA_METJA]] Specifically catalyzes the decarboxylation of L-tyrosine to produce tyramine.<ref>PMID:15715981</ref>
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[https://www.uniprot.org/uniprot/MFNA_METJA MFNA_METJA] Specifically catalyzes the decarboxylation of L-tyrosine to produce tyramine.<ref>PMID:15715981</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 43067]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Tyrosine decarboxylase]]
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[[Category: Methanocaldococcus jannaschii]]
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[[Category: Structural genomic]]
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[[Category: Decarboxylase]]
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[[Category: Jcsg]]
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[[Category: Lyase]]
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[[Category: Np_247014 1]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Pyridoxal phosphate]]
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Current revision

Crystal structure of L-tyrosine decarboxylase MfnA (EC 4.1.1.25) (NP_247014.1) from METHANOCOCCUS JANNASCHII at 2.11 A resolution

PDB ID 3f9t

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