3so5

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Current revision (11:50, 1 February 2023) (edit) (undo)
 
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<StructureSection load='3so5' size='340' side='right'caption='[[3so5]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='3so5' size='340' side='right'caption='[[3so5]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3so5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SO5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SO5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3so5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SO5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SO5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMG:N,N-DIMETHYLGLYCINE'>DMG</scene>, <scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMG:N,N-DIMETHYLGLYCINE'>DMG</scene>, <scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BC065142, Kiaa3016, Lrig3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3so5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3so5 OCA], [https://pdbe.org/3so5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3so5 RCSB], [https://www.ebi.ac.uk/pdbsum/3so5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3so5 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3so5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3so5 OCA], [https://pdbe.org/3so5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3so5 RCSB], [https://www.ebi.ac.uk/pdbsum/3so5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3so5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/LRIG3_MOUSE LRIG3_MOUSE]] Plays a role in craniofacial and inner ear morphogenesis during embryonic development. Acts within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1.<ref>PMID:19004851</ref> <ref>PMID:20126551</ref>
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[https://www.uniprot.org/uniprot/LRIG3_MOUSE LRIG3_MOUSE] Plays a role in craniofacial and inner ear morphogenesis during embryonic development. Acts within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1.<ref>PMID:19004851</ref> <ref>PMID:20126551</ref>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Structural genomic]]
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[[Category: STEMCELL, Partnership for Stem Cell Biology]]
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[[Category: Immunoglobulin]]
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[[Category: Jcsg]]
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[[Category: Partnership for stem cell biology]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Psi-biology]]
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[[Category: Signaling protein]]
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[[Category: Stemcell]]
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Current revision

Crystal structure of an Immunoglobulin I-set domain of Lrig3 protein (Lrig3) from MUS MUSCULUS at 1.70 A resolution

PDB ID 3so5

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