This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


6ofc

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
<StructureSection load='6ofc' size='340' side='right'caption='[[6ofc]], [[Resolution|resolution]] 3.14&Aring;' scene=''>
<StructureSection load='6ofc' size='340' side='right'caption='[[6ofc]], [[Resolution|resolution]] 3.14&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[6ofc]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycto Mycto]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OFC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6OFC FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[6ofc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_CDC1551 Mycobacterium tuberculosis CDC1551]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OFC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OFC FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GLN:GLUTAMINE'>GLN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=SFH:5-O-[(pyridine-3-carbonyl)sulfamoyl]adenosine'>SFH</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GLN:GLUTAMINE'>GLN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=SFH:5-O-[(pyridine-3-carbonyl)sulfamoyl]adenosine'>SFH</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6ofb|6ofb]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ofc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ofc OCA], [https://pdbe.org/6ofc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ofc RCSB], [https://www.ebi.ac.uk/pdbsum/6ofc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ofc ProSAT]</span></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nadE, MT2513 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83331 MYCTO])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_synthase_(glutamine-hydrolyzing) NAD(+) synthase (glutamine-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.5.1 6.3.5.1] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ofc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ofc OCA], [http://pdbe.org/6ofc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ofc RCSB], [http://www.ebi.ac.uk/pdbsum/6ofc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ofc ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/NADE_MYCTO NADE_MYCTO]] Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.[HAMAP-Rule:MF_02090]
+
[https://www.uniprot.org/uniprot/NADE_MYCTO NADE_MYCTO] Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.[HAMAP-Rule:MF_02090]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 18:
</div>
</div>
<div class="pdbe-citations 6ofc" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6ofc" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[NAD synthase|NAD synthase]]
== References ==
== References ==
<references/>
<references/>
Line 26: Line 26:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Mycto]]
+
[[Category: Mycobacterium tuberculosis CDC1551]]
-
[[Category: Chuenchor, W]]
+
[[Category: Chuenchor W]]
-
[[Category: Doukov, T I]]
+
[[Category: Doukov TI]]
-
[[Category: Gerratana, B]]
+
[[Category: Gerratana B]]
-
[[Category: Ammonia tunneling]]
+
-
[[Category: Atp-binding]]
+
-
[[Category: Enzyme]]
+
-
[[Category: Gat]]
+
-
[[Category: Glutaminase]]
+
-
[[Category: Glutamine-amido transferase]]
+
-
[[Category: Glutamine-dependent nad+ synthetase]]
+
-
[[Category: Inhibitor complex]]
+
-
[[Category: Ligase]]
+
-
[[Category: Nad synthetase 1]]
+
-
[[Category: Nad+ synthetase]]
+
-
[[Category: Nucleotide-binding]]
+
-
[[Category: Tuberculosis]]
+

Revision as of 12:02, 1 February 2023

Crystal structure of M. tuberculosis glutamine-dependent NAD+ synthetase complexed with Sulfonamide derivative 1, pyrophosphate, and glutamine

PDB ID 6ofc

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6ofc"
Personal tools