4p0g

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==Crystal structure of MltF from Pseudomonas aeruginosa complexed with bulgecin and muropeptide==
==Crystal structure of MltF from Pseudomonas aeruginosa complexed with bulgecin and muropeptide==
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<StructureSection load='4p0g' size='340' side='right' caption='[[4p0g]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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<StructureSection load='4p0g' size='340' side='right'caption='[[4p0g]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4p0g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P0G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P0G FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4p0g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P0G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4P0G FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMU:BETA-N-ACETYLMURAMIC+ACID'>AMU</scene>, <scene name='pdbligand=BLG:4-O-(4-O-SULFONYL-N-ACETYLGLUCOSAMININYL)-5-METHYLHYDROXY-L-PROLINE-TAURINE'>BLG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMU:BETA-N-ACETYLMURAMIC+ACID'>AMU</scene>, <scene name='pdbligand=BLG:4-O-(4-O-SULFONYL-N-ACETYLGLUCOSAMININYL)-5-METHYLHYDROXY-L-PROLINE-TAURINE'>BLG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4p11|4p11]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4p0g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p0g OCA], [https://pdbe.org/4p0g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4p0g RCSB], [https://www.ebi.ac.uk/pdbsum/4p0g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4p0g ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mltF, PA3764 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p0g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p0g OCA], [http://pdbe.org/4p0g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4p0g RCSB], [http://www.ebi.ac.uk/pdbsum/4p0g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4p0g ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MLTF_PSEAE MLTF_PSEAE]] Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.[HAMAP-Rule:MF_02016]
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[https://www.uniprot.org/uniprot/MLTF_PSEAE MLTF_PSEAE] Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.[HAMAP-Rule:MF_02016]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Pseae]]
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[[Category: Large Structures]]
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[[Category: Redden, E]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Thunnissen, A M.W H]]
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[[Category: Redden E]]
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[[Category: Abc substrate binding-like domain]]
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[[Category: Thunnissen AMWH]]
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[[Category: Glycosyltransferase]]
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[[Category: Lyase]]
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[[Category: Lytic transglycosylase]]
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[[Category: Peptidoglycan]]
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Revision as of 12:35, 1 February 2023

Crystal structure of MltF from Pseudomonas aeruginosa complexed with bulgecin and muropeptide

PDB ID 4p0g

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