4p5b
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='4p5b' size='340' side='right'caption='[[4p5b]], [[Resolution|resolution]] 2.27Å' scene=''> | <StructureSection load='4p5b' size='340' side='right'caption='[[4p5b]], [[Resolution|resolution]] 2.27Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4p5b]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4p5b]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_asoensis Streptomyces asoensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P5B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4P5B FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BRU:5-BROMO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>BRU</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BRU:5-BROMO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>BRU</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4p5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p5b OCA], [https://pdbe.org/4p5b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4p5b RCSB], [https://www.ebi.ac.uk/pdbsum/4p5b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4p5b ProSAT]</span></td></tr> | |
| - | + | ||
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/C1IC19_9ACTN C1IC19_9ACTN] Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.[HAMAP-Rule:MF_01408] |
==See Also== | ==See Also== | ||
| - | *[[Thymidylate synthase|Thymidylate synthase]] | + | *[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: As 4 1602]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Chen | + | [[Category: Streptomyces asoensis]] |
| - | [[Category: Deng | + | [[Category: Chen W]] |
| - | [[Category: Li | + | [[Category: Deng Z]] |
| - | [[Category: Li | + | [[Category: Li J]] |
| - | [[Category: Xia | + | [[Category: Li Y]] |
| - | [[Category: Zhou | + | [[Category: Xia Z]] |
| - | + | [[Category: Zhou J]] | |
| - | + | ||
| - | + | ||
| - | + | ||
Revision as of 12:42, 1 February 2023
Crystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi bound with 5-Br dUMP
| |||||||||||
Categories: Large Structures | Streptomyces asoensis | Chen W | Deng Z | Li J | Li Y | Xia Z | Zhou J
