4pa8

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<StructureSection load='4pa8' size='340' side='right'caption='[[4pa8]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
<StructureSection load='4pa8' size='340' side='right'caption='[[4pa8]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4pa8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PA8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PA8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4pa8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PA8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PA8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2K6:(3R)-3-(4-METHOXYPHENYL)-5-OXOHEXANENITRILE'>2K6</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2K6:(3R)-3-(4-METHOXYPHENYL)-5-OXOHEXANENITRILE'>2K6</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4a29|4a29]], [[4a2s|4a2s]], [[4a2r|4a2r]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pa8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pa8 OCA], [https://pdbe.org/4pa8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pa8 RCSB], [https://www.ebi.ac.uk/pdbsum/4pa8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pa8 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pa8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pa8 OCA], [http://pdbe.org/4pa8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pa8 RCSB], [http://www.ebi.ac.uk/pdbsum/4pa8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pa8 ProSAT]</span></td></tr>
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</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 35091]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Beck, T]]
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[[Category: Saccharolobus solfataricus]]
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[[Category: Hilvert, D]]
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[[Category: Beck T]]
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[[Category: Pi, X Garrabou]]
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[[Category: Garrabou Pi X]]
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[[Category: Aldolase]]
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[[Category: Hilvert D]]
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[[Category: Artificial catalyst]]
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[[Category: Computer-aided design]]
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[[Category: De novo protein]]
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[[Category: Directed evolution]]
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[[Category: Enzyme design]]
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[[Category: Enzyme-product analog complex]]
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[[Category: Hydrolase]]
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[[Category: Michael addition]]
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[[Category: Protein engineering]]
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[[Category: Retro-aldolase]]
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[[Category: Substrate specificity]]
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[[Category: Tim-barrel fold]]
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Revision as of 12:49, 1 February 2023

Crystal structure of a de novo retro-aldolase catalyzing asymmetric Michael additions, with a covalently bound product analog

PDB ID 4pa8

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