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4pc2

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==Elongation factor Tu:Ts complex with a bound GDP==
==Elongation factor Tu:Ts complex with a bound GDP==
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<StructureSection load='4pc2' size='340' side='right' caption='[[4pc2]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='4pc2' size='340' side='right'caption='[[4pc2]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4pc2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895] and [http://en.wikipedia.org/wiki/Ecodh Ecodh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PC2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PC2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4pc2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Escherichia_coli_str._K-12_substr._DH10B Escherichia coli str. K-12 substr. DH10B]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PC2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pc1|4pc1]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pc2 OCA], [https://pdbe.org/4pc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pc2 RCSB], [https://www.ebi.ac.uk/pdbsum/4pc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pc2 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tufA, tuf, ECDH10B_3514 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=316385 ECODH]), tsf, BN17_45931, ECs0172, LF82_2325 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pc2 OCA], [http://pdbe.org/4pc2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pc2 RCSB], [http://www.ebi.ac.uk/pdbsum/4pc2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pc2 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/B1X6I9_ECODH B1X6I9_ECODH]] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.[HAMAP-Rule:MF_00118] [[http://www.uniprot.org/uniprot/C3TPM7_ECOLX C3TPM7_ECOLX]] Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.[HAMAP-Rule:MF_00050][RuleBase:RU000642]
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[https://www.uniprot.org/uniprot/A0A0M3KKV1_ECODH A0A0M3KKV1_ECODH] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.[HAMAP-Rule:MF_00118]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Elongation factor|Elongation factor]]
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*[[Elongation factor 3D structures|Elongation factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: Ecodh]]
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[[Category: Escherichia coli str. K-12 substr. DH10B]]
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[[Category: Thirup, S S]]
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[[Category: Large Structures]]
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[[Category: Elongation factor t]]
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[[Category: Thirup SS]]
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[[Category: Elongation factor tu]]
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[[Category: G:gef:gdp complex]]
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[[Category: Translation]]
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Revision as of 12:51, 1 February 2023

Elongation factor Tu:Ts complex with a bound GDP

PDB ID 4pc2

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