8fwk

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "8fwk" [edit=sysop:move=sysop])
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 8fwk is ON HOLD
+
==CryoEM structure of Human ABCB6 Transporter==
-
 
+
<StructureSection load='8fwk' size='340' side='right'caption='[[8fwk]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
-
Authors: Shaik, M.M., Myasnikov, A.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[8fwk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FWK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FWK FirstGlance]. <br>
-
Description: CryoEM structure of Human ABCB6 Transporter
+
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8fwk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8fwk OCA], [https://pdbe.org/8fwk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8fwk RCSB], [https://www.ebi.ac.uk/pdbsum/8fwk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8fwk ProSAT]</span></td></tr>
-
[[Category: Unreleased Structures]]
+
</table>
-
[[Category: Shaik, M.M]]
+
== Disease ==
-
[[Category: Myasnikov, A]]
+
[https://www.uniprot.org/uniprot/ABCB6_HUMAN ABCB6_HUMAN] Ocular coloboma;Dyschromatosis universalis;Colobomatous microphthalmia. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. ABCB6 mutations are involved in familial pseudohyperkalemia, a dominantly inherited condition characterized by increased serum potassium levels, measured in whole-blood specimens stored at or below room temperature. This condition is not accompanied by clinical symptoms or biological signs except for borderline abnormalities of red cell shape (PubMed:23180570).<ref>PMID:23180570</ref>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/ABCB6_HUMAN ABCB6_HUMAN] Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis.<ref>PMID:10837493</ref> <ref>PMID:17006453</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Myasnikov A]]
 +
[[Category: Shaik MM]]

Revision as of 06:49, 8 February 2023

CryoEM structure of Human ABCB6 Transporter

PDB ID 8fwk

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/8fwk"
Personal tools