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4pp8

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==Crystal structure of murine NK cell ligand RAE-1 beta in complex with NKG2D==
==Crystal structure of murine NK cell ligand RAE-1 beta in complex with NKG2D==
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<StructureSection load='4pp8' size='340' side='right' caption='[[4pp8]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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<StructureSection load='4pp8' size='340' side='right'caption='[[4pp8]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4pp8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1jsk 1jsk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PP8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PP8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4pp8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1jsk 1jsk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PP8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PP8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Klrk1, Nkg2d, RAE-1 BETA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice]), NKG2D, Raet1b ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pp8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pp8 OCA], [https://pdbe.org/4pp8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pp8 RCSB], [https://www.ebi.ac.uk/pdbsum/4pp8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pp8 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pp8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pp8 OCA], [http://pdbe.org/4pp8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pp8 RCSB], [http://www.ebi.ac.uk/pdbsum/4pp8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pp8 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NKG2D_MOUSE NKG2D_MOUSE]] Receptor for RAET1A, RAET1B, RAET1C, RAET1D, RAET1E, H60 and MULT1. Involved in the immune surveillance exerted by T and B lymphocytes.<ref>PMID:12370332</ref> [[http://www.uniprot.org/uniprot/RAE1B_MOUSE RAE1B_MOUSE]] Acts as a ligand for NKG2D.<ref>PMID:10894171</ref>
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[https://www.uniprot.org/uniprot/NKG2D_MOUSE NKG2D_MOUSE] Receptor for RAET1A, RAET1B, RAET1C, RAET1D, RAET1E, H60 and MULT1. Involved in the immune surveillance exerted by T and B lymphocytes.<ref>PMID:12370332</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Li, P]]
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[[Category: Mus musculus]]
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[[Category: Strong, R K]]
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[[Category: Li P]]
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[[Category: Immune system]]
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[[Category: Strong RK]]
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[[Category: Mhc-i platform]]
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[[Category: Murine nk cell ligand]]
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[[Category: Nkg2d]]
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[[Category: Rae-1 beta]]
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Current revision

Crystal structure of murine NK cell ligand RAE-1 beta in complex with NKG2D

PDB ID 4pp8

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