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4q2e

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==CRYSTAL STRUCTURE OF AN INTRAMEMBRANE CDP-DAG SYNTHETASE CENTRAL FOR PHOSPHOLIPID BIOSYNTHESIS (S200C/S258C, active mutant)==
==CRYSTAL STRUCTURE OF AN INTRAMEMBRANE CDP-DAG SYNTHETASE CENTRAL FOR PHOSPHOLIPID BIOSYNTHESIS (S200C/S258C, active mutant)==
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<StructureSection load='4q2e' size='340' side='right' caption='[[4q2e]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
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<StructureSection load='4q2e' size='340' side='right'caption='[[4q2e]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4q2e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thema Thema]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q2E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q2E FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4q2e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q2E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q2E FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cdsA, TM_1397 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243274 THEMA])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q2e OCA], [https://pdbe.org/4q2e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q2e RCSB], [https://www.ebi.ac.uk/pdbsum/4q2e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q2e ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphatidate_cytidylyltransferase Phosphatidate cytidylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.41 2.7.7.41] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q2e OCA], [http://pdbe.org/4q2e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q2e RCSB], [http://www.ebi.ac.uk/pdbsum/4q2e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q2e ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CDSA_THEMA CDSA_THEMA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Phosphatidate cytidylyltransferase]]
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[[Category: Large Structures]]
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[[Category: Thema]]
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[[Category: Thermotoga maritima MSB8]]
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[[Category: Liu, X]]
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[[Category: Liu X]]
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[[Category: Liu, Z]]
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[[Category: Liu Z]]
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[[Category: Wu, J]]
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[[Category: Wu J]]
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[[Category: Yin, Y]]
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[[Category: Yin Y]]
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[[Category: Cdsa fold]]
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[[Category: Ctp and phosphatidic acid binding]]
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[[Category: Intramembrane enzyme]]
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[[Category: Membrane]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Phospholipid biosynthesis lipid metabolism]]
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[[Category: Transferase]]
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Revision as of 07:41, 8 February 2023

CRYSTAL STRUCTURE OF AN INTRAMEMBRANE CDP-DAG SYNTHETASE CENTRAL FOR PHOSPHOLIPID BIOSYNTHESIS (S200C/S258C, active mutant)

PDB ID 4q2e

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