4q32
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and C91== | ==Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and C91== | ||
| - | <StructureSection load='4q32' size='340' side='right' caption='[[4q32]], [[Resolution|resolution]] 2.79Å' scene=''> | + | <StructureSection load='4q32' size='340' side='right'caption='[[4q32]], [[Resolution|resolution]] 2.79Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4q32]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4q32]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens_ATCC_13124 Clostridium perfringens ATCC 13124]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q32 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q32 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C91:N-(NAPHTHALEN-2-YL)-2-[2-(PYRIDIN-2-YL)-1H-BENZIMIDAZOL-1-YL]ACETAMIDE'>C91</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C91:N-(NAPHTHALEN-2-YL)-2-[2-(PYRIDIN-2-YL)-1H-BENZIMIDAZOL-1-YL]ACETAMIDE'>C91</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q32 OCA], [https://pdbe.org/4q32 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q32 RCSB], [https://www.ebi.ac.uk/pdbsum/4q32 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q32 ProSAT]</span></td></tr> | |
| - | + | ||
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/A0A0H2YRZ7_CLOP1 A0A0H2YRZ7_CLOP1] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964] |
| + | |||
| + | ==See Also== | ||
| + | *[[Inosine monophosphate dehydrogenase 3D structures|Inosine monophosphate dehydrogenase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Clostridium perfringens ATCC 13124]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Anderson | + | [[Category: Anderson WF]] |
| - | + | [[Category: Gollapalli DR]] | |
| - | [[Category: Gollapalli | + | [[Category: Gorla SK]] |
| - | [[Category: Gorla | + | [[Category: Gu M]] |
| - | [[Category: Gu | + | [[Category: Hedstrom L]] |
| - | [[Category: Hedstrom | + | [[Category: Joachimiak A]] |
| - | [[Category: Joachimiak | + | [[Category: Kim Y]] |
| - | [[Category: Kim | + | [[Category: Makowska-Grzyska M]] |
| - | [[Category: Makowska-Grzyska | + | [[Category: Maltseva N]] |
| - | [[Category: Maltseva | + | [[Category: Mandapati K]] |
| - | [[Category: Mandapati | + | [[Category: Mulligan R]] |
| - | [[Category: Mulligan | + | [[Category: Zhang M]] |
| - | [[Category: Zhang | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Revision as of 07:41, 8 February 2023
Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and C91
| |||||||||||
