7wvb

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'''Unreleased structure'''
 
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The entry 7wvb is ON HOLD until Paper Publication
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==Human Fructose-1,6-bisphosphatase 1 mutant R50A in APO R-state==
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<StructureSection load='7wvb' size='340' side='right'caption='[[7wvb]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
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Authors: Chen, Y., Zhang, J., Li, C., Cao, Y.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7wvb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WVB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WVB FirstGlance]. <br>
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Description: Human Fructose-1,6-bisphosphatase 1 mutant R50A in APO R-state
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wvb OCA], [https://pdbe.org/7wvb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wvb RCSB], [https://www.ebi.ac.uk/pdbsum/7wvb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wvb ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Cao, Y]]
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== Disease ==
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[[Category: Li, C]]
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[https://www.uniprot.org/uniprot/F16P1_HUMAN F16P1_HUMAN] Defects in FBP1 are the cause of fructose-1,6-bisphosphatase deficiency (FBPD) [MIM:[https://omim.org/entry/229700 229700]. FBPD is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis (lactacidemia) in newborn infants or young children.<ref>PMID:9382095</ref> <ref>PMID:12126934</ref>
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[[Category: Zhang, J]]
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== Function ==
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[[Category: Chen, Y]]
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[https://www.uniprot.org/uniprot/F16P1_HUMAN F16P1_HUMAN]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Cao Y]]
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[[Category: Chen Y]]
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[[Category: Li C]]
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[[Category: Zhang J]]

Revision as of 10:23, 15 February 2023

Human Fructose-1,6-bisphosphatase 1 mutant R50A in APO R-state

PDB ID 7wvb

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