1jx7
From Proteopedia
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'''Crystal structure of ychN protein from E.coli''' | '''Crystal structure of ychN protein from E.coli''' | ||
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[[Category: Shin, D H.]] | [[Category: Shin, D H.]] | ||
[[Category: Yokota, H.]] | [[Category: Yokota, H.]] | ||
| - | [[Category: | + | [[Category: Berkeley structural genomics center]] |
| - | [[Category: | + | [[Category: Bsgc structure funded by nih]] |
| - | [[Category: | + | [[Category: Hexamer]] |
| - | [[Category: | + | [[Category: New fold]] |
| - | [[Category: | + | [[Category: Protein structure initiative]] |
| - | [[Category: | + | [[Category: Psi]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 22:02:07 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 19:02, 2 May 2008
Crystal structure of ychN protein from E.coli
Overview
The crystal structure of a conserved hypothetical protein from Escherichia coli has been determined using X-ray crystallography. The protein belongs to the Cluster of Orthologous Group COG1553 (National Center for Biotechnology Information database, NLM, NIH), for which there was no structural information available until now. Structural homology search with DALI algorism indicated that this protein has a new fold with no obvious similarity to those of other proteins with known three-dimensional structures. The protein quaternary structure consists of a dimer of trimers, which makes a characteristic cylinder shape. There is a large closed cavity with approximate dimensions of 16 A x 16 A x 20 A in the center of the hexameric structure. Six putative active sites are positioned along the equatorial surface of the hexamer. There are several highly conserved residues including two possible functional cysteines in the putative active site. The possible molecular function of the protein is discussed.
About this Structure
1JX7 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
Crystal structure of a conserved hypothetical protein from Escherichia coli., Shin DH, Yokota H, Kim R, Kim SH, J Struct Funct Genomics. 2002;2(1):53-66. PMID:12836674 Page seeded by OCA on Fri May 2 22:02:07 2008
