2lm1
From Proteopedia
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==Solution NMR Structure of Lysine-specific demethylase lid from Drosophila melanogaster, Northeast Structural Genomics Consortium Target FR824D== | ==Solution NMR Structure of Lysine-specific demethylase lid from Drosophila melanogaster, Northeast Structural Genomics Consortium Target FR824D== | ||
| - | <StructureSection load='2lm1' size='340' side='right'caption='[[2lm1 | + | <StructureSection load='2lm1' size='340' side='right'caption='[[2lm1]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2lm1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2lm1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LM1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LM1 FirstGlance]. <br> |
| - | </td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lm1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lm1 OCA], [https://pdbe.org/2lm1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lm1 RCSB], [https://www.ebi.ac.uk/pdbsum/2lm1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lm1 ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lm1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lm1 OCA], [https://pdbe.org/2lm1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lm1 RCSB], [https://www.ebi.ac.uk/pdbsum/2lm1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lm1 ProSAT]</span></td></tr> | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/KDM5_DROME KDM5_DROME] Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Specifically demethylates trimethylated H3 'Lys-4'. Required for the correct regulation of homeotic genes during development.<ref>PMID:11014813</ref> <ref>PMID:17311883</ref> <ref>PMID:17351631</ref> <ref>PMID:17351630</ref> | |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Drosophila melanogaster]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Acton | + | [[Category: Acton TB]] |
| - | + | [[Category: Everett JK]] | |
| - | [[Category: Everett | + | [[Category: Kohan E]] |
| - | [[Category: Kohan | + | [[Category: Kusch T]] |
| - | [[Category: Kusch | + | [[Category: Lee D]] |
| - | [[Category: Lee | + | [[Category: Mills JL]] |
| - | [[Category: Mills | + | [[Category: Montelione GT]] |
| - | [[Category: Montelione | + | [[Category: Sahdev S]] |
| - | + | [[Category: Szyperski T]] | |
| - | [[Category: Sahdev | + | [[Category: Xiao R]] |
| - | [[Category: Szyperski | + | |
| - | [[Category: Xiao | + | |
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Revision as of 11:07, 15 February 2023
Solution NMR Structure of Lysine-specific demethylase lid from Drosophila melanogaster, Northeast Structural Genomics Consortium Target FR824D
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Categories: Drosophila melanogaster | Large Structures | Acton TB | Everett JK | Kohan E | Kusch T | Lee D | Mills JL | Montelione GT | Sahdev S | Szyperski T | Xiao R
