2lna

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==Solution NMR Structure of the mitochondrial inner membrane domain (residues 164-251), FtsH_ext, from the paraplegin-like protein AFG3L2 from Homo sapiens, Northeast Structural Genomics Consortium Target HR6741A==
==Solution NMR Structure of the mitochondrial inner membrane domain (residues 164-251), FtsH_ext, from the paraplegin-like protein AFG3L2 from Homo sapiens, Northeast Structural Genomics Consortium Target HR6741A==
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<StructureSection load='2lna' size='340' side='right'caption='[[2lna]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2lna' size='340' side='right'caption='[[2lna]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2lna]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LNA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LNA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2lna]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LNA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LNA FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AFG3L2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lna OCA], [https://pdbe.org/2lna PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lna RCSB], [https://www.ebi.ac.uk/pdbsum/2lna PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lna ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lna OCA], [https://pdbe.org/2lna PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lna RCSB], [https://www.ebi.ac.uk/pdbsum/2lna PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lna ProSAT]</span></td></tr>
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</table>
</table>
== Disease ==
== Disease ==
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[[https://www.uniprot.org/uniprot/AFG32_HUMAN AFG32_HUMAN]] Spinocerebellar ataxia type 28;Early-onset spastic ataxia-neuropathy syndrome. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
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[https://www.uniprot.org/uniprot/AFG32_HUMAN AFG32_HUMAN] Spinocerebellar ataxia type 28;Early-onset spastic ataxia-neuropathy syndrome. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/AFG32_HUMAN AFG32_HUMAN]] ATP-dependent protease which is essential for axonal development (By similarity).
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[https://www.uniprot.org/uniprot/AFG32_HUMAN AFG32_HUMAN] ATP-dependent protease which is essential for axonal development (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Acton, T B]]
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[[Category: Acton TB]]
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[[Category: Everett, J K]]
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[[Category: Everett JK]]
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[[Category: Janua, H]]
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[[Category: Janua H]]
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[[Category: Kennedy, M A]]
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[[Category: Kennedy MA]]
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[[Category: Kohan, E]]
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[[Category: Kohan E]]
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[[Category: Lee, H]]
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[[Category: Lee H]]
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[[Category: MPP, Mitochondrial Protein Partnership]]
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[[Category: Montelione GT]]
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[[Category: Montelione, G T]]
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[[Category: Prestegard JH]]
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[[Category: Structural genomic]]
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[[Category: Ramelot TA]]
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[[Category: Prestegard, J H]]
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[[Category: Shastry R]]
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[[Category: Ramelot, T A]]
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[[Category: Xiao R]]
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[[Category: Shastry, R]]
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[[Category: Yang Y]]
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[[Category: Xiao, R]]
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[[Category: Yang, Y]]
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[[Category: Hydrolase]]
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[[Category: Mitochondrial protein partnership]]
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[[Category: Mpp]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Psi-biology]]
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Revision as of 11:08, 15 February 2023

Solution NMR Structure of the mitochondrial inner membrane domain (residues 164-251), FtsH_ext, from the paraplegin-like protein AFG3L2 from Homo sapiens, Northeast Structural Genomics Consortium Target HR6741A

PDB ID 2lna

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