4qbx
From Proteopedia
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| <StructureSection load='4qbx' size='340' side='right'caption='[[4qbx]], [[Resolution|resolution]] 0.98Å' scene=''> | <StructureSection load='4qbx' size='340' side='right'caption='[[4qbx]], [[Resolution|resolution]] 0.98Å' scene=''> | ||
| == Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4qbx]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4qbx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QBX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QBX FirstGlance]. <br> | 
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=30L:{5-FLUORO-2-[(3-NITROBENZYL)CARBAMOYL]PHENOXY}ACETIC+ACID'>30L</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=30L:{5-FLUORO-2-[(3-NITROBENZYL)CARBAMOYL]PHENOXY}ACETIC+ACID'>30L</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | 
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qbx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qbx OCA], [https://pdbe.org/4qbx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qbx RCSB], [https://www.ebi.ac.uk/pdbsum/4qbx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qbx ProSAT]</span></td></tr> | |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
| </table> | </table> | ||
| == Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. | 
| ==See Also== | ==See Also== | ||
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| __TOC__ | __TOC__ | ||
| </StructureSection> | </StructureSection> | ||
| - | [[Category:  | + | [[Category: Homo sapiens]] | 
| - | + | ||
| [[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Heine | + | [[Category: Heine A]] | 
| - | [[Category: Klebe | + | [[Category: Klebe G]] | 
| - | [[Category: Rechlin | + | [[Category: Rechlin C]] | 
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Revision as of 11:22, 15 February 2023
Human Aldose Reductase complexed with a ligand with an IDD structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid) at 0.98 A
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