4qez

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==Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Bacillus anthracis==
==Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Bacillus anthracis==
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<StructureSection load='4qez' size='340' side='right' caption='[[4qez]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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<StructureSection load='4qez' size='340' side='right'caption='[[4qez]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4qez]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_cereus_var._anthracis"_(cohn_1872)_smith_et_al._1946 "bacillus cereus var. anthracis" (cohn 1872) smith et al. 1946]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QEZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QEZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4qez]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QEZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mtnN, BA_4602, GBAA_4602, BAS4270 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 "Bacillus cereus var. anthracis" (Cohn 1872) Smith et al. 1946])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qez OCA], [https://pdbe.org/4qez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qez RCSB], [https://www.ebi.ac.uk/pdbsum/4qez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qez ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosylhomocysteine_nucleosidase Adenosylhomocysteine nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.9 3.2.2.9] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qez OCA], [http://pdbe.org/4qez PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qez RCSB], [http://www.ebi.ac.uk/pdbsum/4qez PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qez ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MTNN_BACAN MTNN_BACAN]] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity).
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[https://www.uniprot.org/uniprot/MTNN_BACAN MTNN_BACAN] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Adenosylhomocysteine nucleosidase]]
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[[Category: Bacillus anthracis]]
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[[Category: Devi, S]]
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[[Category: Large Structures]]
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[[Category: Gourinath, S]]
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[[Category: Abdul Rehman SA]]
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[[Category: Rehman, S A.Abdul]]
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[[Category: Devi S]]
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[[Category: Tarique, K F]]
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[[Category: Gourinath S]]
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[[Category: Amino-acid biosynthesis]]
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[[Category: Tarique KF]]
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[[Category: Hydrolase]]
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[[Category: Methionine biosynthesis]]
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Revision as of 11:27, 15 February 2023

Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Bacillus anthracis

PDB ID 4qez

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