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4qkz
From Proteopedia
(Difference between revisions)
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<StructureSection load='4qkz' size='340' side='right'caption='[[4qkz]], [[Resolution|resolution]] 1.20Å' scene=''> | <StructureSection load='4qkz' size='340' side='right'caption='[[4qkz]], [[Resolution|resolution]] 1.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4qkz]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4qkz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QKZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QKZ FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=QZK:{[(BIPHENYL-4-YLSULFONYL)AMINO]METHANEDIYL}BIS(PHOSPHONIC+ACID)'>QZK</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=QZK:{[(BIPHENYL-4-YLSULFONYL)AMINO]METHANEDIYL}BIS(PHOSPHONIC+ACID)'>QZK</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qkz OCA], [https://pdbe.org/4qkz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qkz RCSB], [https://www.ebi.ac.uk/pdbsum/4qkz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qkz ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/MMP8_HUMAN MMP8_HUMAN] Can degrade fibrillar type I, II, and III collagens. |
==See Also== | ==See Also== | ||
| - | *[[Matrix metalloproteinase|Matrix metalloproteinase]] | + | *[[Matrix metalloproteinase 3D structures|Matrix metalloproteinase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Capelli D]] | |
| - | [[Category: Capelli | + | [[Category: Montanari R]] |
| - | [[Category: Montanari | + | [[Category: Pochetti G]] |
| - | [[Category: Pochetti | + | [[Category: Tortorella P]] |
| - | [[Category: Tortorella | + | |
| - | + | ||
| - | + | ||
Revision as of 11:34, 15 February 2023
X-ray structure of the catalytic domain of MMP-8 with the inhibitor ML115
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